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v2.2 contact about news diagnosing dird browse the drug-induced respiratory disease website philippe camus, m.d. dijon, france browse by » drugs patterns list all a b c d e f g h i j k l m n o p q r s t u v w x y z abacavir i.a i - interstitial/parenchymal lung disease i.a - pneumonitis (ild), acute, severe (see also under ards) i.f i - interstitial/parenchymal lung disease i.f - acute fibrinous organizing pneumonia (afop) ii.a ii - pulmonary edema - ards - acute respiratory failure ii.a - pulmonary edema, noncardiogenic (ncpe) ii.b ii - pulmonary edema - ards - acute respiratory failure ii.b - ards iv.d iv - airway involvement iv.d - cough (lone) x.a x - systemic conditions, syndromes and reactions x.a - dress (drug rash eosinophilia and hypersensitivity syndrome) x.f x - systemic conditions, syndromes and reactions x.f - anaphylaxis xv.d xv - pulmonary pathology xv.d - path: acute fibrinous organizing pneumonia (afop-pattern) (see also if) 2 abatacept i.a i - interstitial/parenchymal lung disease i.a - pneumonitis (ild), acute, severe (see also under ards) ii.b ii - pulmonary edema - ards - acute respiratory failure ii.b - ards x.e x - systemic conditions, syndromes and reactions x.e - autoimmunity - autoimmune conditions 2 abciximab iii.a iii - pulmonary hemorrhage iii.a - diffuse alveolar hemorrhage (dah) v.n v - pleural and/or pericardial involvement v.n - hemopericardium - bloody pericardial effusion x.f x - systemic conditions, syndromes and reactions x.f - anaphylaxis 3 abiraterone i.a i - interstitial/parenchymal lung disease i.a - pneumonitis (ild), acute, severe (see also under ards) i.b i - interstitial/parenchymal lung disease i.b - pneumonitis (ild) x.r x - systemic conditions, syndromes and reactions x.r - fluid retention 2 abused drugs/substances (illicit-, street drugs - iv/inhaled) i.j i - interstitial/parenchymal lung disease i.j - exogenous lipoid pneumonia i.m i - interstitial/parenchymal lung disease i.m - ild with a granulomatous component i.s i - interstitial/parenchymal lung disease i.s - a mass or masses i.t i - interstitial/parenchymal lung disease i.t - pneumoconiosis, talcosis ii.b ii - pulmonary edema - ards - acute respiratory failure ii.b - ards iii.a iii - pulmonary hemorrhage iii.a - diffuse alveolar hemorrhage (dah) iv.a iv - airway involvement iv.a - bronchospasm - asthma iv.f iv - airway involvement iv.f - severe, catastrophic asthma attack (can be fatal) iv.g iv - airway involvement iv.g - syncope - cough syncope v.f v - pleural and/or pericardial involvement v.f - pneumothorax v.q v - pleural and/or pericardial involvement v.q - empyema vi.b vi - pulmonary vasculopathy vi.b - pulmonary arterial hypertension vi.c vi - pulmonary vasculopathy vi.c - pulmonary veno-occlusive disease vi.g vi - pulmonary vasculopathy vi.g - foreign body vasculopathy (excipient lung disease) vi.i vi - pulmonary vasculopathy vi.i - acute pulmonary hypertension vi.j vi - pulmonary vasculopathy vi.j - mercury pulmonary embolism vi.r vi - pulmonary vasculopathy vi.r - septic pulmonary embolism vi.t vi - pulmonary vasculopathy vi.t - pulmonary artery aneurysm(s) vii.h vii - mediastinal involvement vii.h - pneumomediastinum viii.c viii - upper, central, large airway involvement viii.c - upper airway obstruction other than angioedema or hematoma viii.d viii - upper, central, large airway involvement viii.d - thermal (burns, frostbite), chemical, or caustic facial and/or airway injury ix.a ix - neuromuscular / cns involvement - disordered breathing during sleep ix.a - diaphragm/inspiratory muscle weakness/paralysis (w/wo arf) ix.s ix - neuromuscular / cns involvement - disordered breathing during sleep ix.s - botulism - wound botulism x.u x - systemic conditions, syndromes and reactions x.u - multiple organ dysfunction/failure (mods/mof) x.ac x - systemic conditions, syndromes and reactions x.ac - anti-gbm antibody disease (goodpasture-like) or flare of xi.b xi - miscellaneous xi.b - chest pain (acute - subacute) xi.g xi - miscellaneous xi.g - aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility) xi.m xi - miscellaneous xi.m - pulmonary emphysema - lung cysts or bullae xi.r xi - miscellaneous xi.r - death following exposure or poisoning xii.i xii - cardiovascular involvement / toxicity xii.i - endocarditis (infective) xii.v xii - cardiovascular involvement / toxicity xii.v - hypertrophic cardiomyopathy xv.q xv - pulmonary pathology xv.q - path: foreign body deposits/reaction xv.s xv - pulmonary pathology xv.s - path: pneumoconiosis (silicosis, talcosis, talcoma) xv.ag xv - pulmonary pathology xv.ag - path: foreign body embolism, microangiopathy, vasculopathy xv.al xv - pulmonary pathology xv.al - path: pulmonary hypertension incl. angiomatoid vasculopathy xvi.v xvi - imaging xvi.v - imaging: diffuse centrilobular micronodules xvi.ab xvi - imaging xvi.ab - imaging: cavitating lung nodules (see also iq, xis, xiii, xviaa and xviip) xvi.ae xvi - imaging xvi.ae - imaging: a pattern similar to progressive massive fibrosis (pmf) xvi.af xvi - imaging xvi.af - imaging: lung cysts or bullae (see also xvi ah/bf) xvii.a xvii - infections & related conditions xvii.a - pneumonia - respiratory tract infection xvii.b xvii - infections & related conditions xvii.b - opportunistic pulmonary/systemic infection xvii.g xvii - infections & related conditions xvii.g - tuberculosis (pulmonary, extrapulmonary, reactivation or de novo) xvii.p xvii - infections & related conditions xvii.p - lung abscess/abscesses (see also vir) xvii.s xvii - infections & related conditions xvii.s - sternoclavicular septic arthritis xvii.u xvii - infections & related conditions xvii.u - epidural abscess 5 acebrophylline viii.a viii - upper, central, large airway involvement viii.a - angioedema (may cause uao & asphyxia) 1 acebutolol i.b i - interstitial/parenchymal lung disease i.b - pneumonitis (ild) i.d i - interstitial/parenchymal lung disease i.d - organizing pneumonia (a pattern consistent with) v.a v - pleural and/or pericardial involvement v.a - pleural effusion v.d v - pleural and/or pericardial involvement v.d - pleural/pericardial effusion, ana positive (di lupus) x.y x - systemic conditions, syndromes and reactions x.y - subclinical ana positivity 2 acenocoumarol viii.b viii - upper, central, large airway involvement viii.b - hematoma causing upper airway obstruction 1 acepromazine ix.d ix - neuromuscular / cns involvement - disordered breathing during sleep ix.d - ventilatory depression-hypoventilation (may cause arf). see also xie 1 acetanilide xiv.b xiv - hemoglobinopathies-abnormal hemoglobins states (acquired) xiv.b - sulfhemoglobinemia 1 acetazolamide ii.a ii - pulmonary edema - ards - acute respiratory failure ii.a - pulmonary edema, noncardiogenic (ncpe) ix.a ix - neuromuscular / cns involvement - disordered breathing during sleep ix.a - diaphragm/inspiratory muscle weakness/paralysis (w/wo arf) x.f x - systemic conditions, syndromes and reactions x.f - anaphylaxis xi.d xi - miscellaneous xi.d - metabolic acidosis (incl. lactic-). may cause dyspnea xii.n xii - cardiovascular involvement / toxicity xii.n - hypotension, shock, cardiovascular collapse 3 acetylcholine xii.g xii - cardiovascular involvement / toxicity xii.g - myocardial ischemia, coronary artery disease, myocardial infarction 1 acetylcysteine (n-acetylcysteine) i.y i - interstitial/parenchymal lung disease i.y - progression, acceleration or exacerbation of preexisting ild/fibrosis iv.a iv - airway involvement iv.a - bronchospasm - asthma viii.a viii - upper, central, large airway involvement viii.a - angioedema (may cause uao & asphyxia) x.f x - systemic conditions, syndromes and reactions x.f - anaphylaxis 2 acetylfentanyl ii.a ii - pulmonary edema - ards - acute respiratory failure ii.a - pulmonary edema, noncardiogenic (ncpe) ix.d ix - neuromuscular / cns involvement - disordered breathing during sleep ix.d - ventilatory depression-hypoventilation (may cause arf). see also xie xi.r xi - miscellaneous xi.r - death following exposure or poisoning 1 acitretin ii.b ii - pulmonary edema - ards - acute respiratory failure ii.b - ards x.c x - systemic conditions, syndromes and reactions x.c - capillary/vascular leak syndrome (cls) (see also under xr) 1 aconite xii.l xii - cardiovascular involvement / toxicity xii.l - cardiac arrhythmias or dysrhythmias (af, vt, vf, tdp) xii.w xii - cardiovascular involvement / toxicity xii.w - asystole 2 aconitine xii.l xii - cardiovascular involvement / toxicity xii.l - cardiac arrhythmias or dysrhythmias (af, vt, vf, tdp) 1 acrylfentanyl 1 acupuncture v.e v - pleural and/or pericardial involvement v.e - hemothorax - serosanguineous pleural effusion v.f v - pleural and/or pericardial involvement v.f - pneumothorax v.h v - pleural and/or pericardial involvement v.h - chylothorax 3 acyclovir i.b i - interstitial/parenchymal lung disease i.b - pneumonitis (ild) v.a v - pleural and/or pericardial involvement v.a - pleural effusion 1 adalimumab i.a i - interstitial/parenchymal lung disease i.a - pneumonitis (ild), acute, severe (see also under ards) i.b i - interstitial/parenchymal lung disease i.b - pneumonitis (ild) i.c i - interstitial/parenchymal lung disease i.c - eosinophilic pneumonia (pulmonary infiltrates and eosinophilia) i.d i - interstitial/parenchymal lung disease i.d - organizing pneumonia (a pattern consistent with) i.g i - interstitial/parenchymal lung disease i.g - pulmonary fibrosis i.m i - interstitial/parenchymal lung disease i.m - ild with a granulomatous component i.w i - interstitial/parenchymal lung disease i.w - rapidly progressive ild or pulmonary fibrosis (hamman-rich syndrome) ii.b ii - pulmonary edema - ards - acute respiratory failure ii.b - ards iv.a iv - airway involvement iv.a - bronchospasm - asthma v.d v - pleural and/or pericardial involvement v.d - pleural/pericardial effusion, ana positive (di lupus) v.m v - pleural and/or pericardial involvement v.m - pleuropericardial effusion (ana unknown or negative) ix.j ix - neuromuscular / cns involvement - disordered breathing during sleep ix.j - phrenic nerve injury - hemidiaphragmatic paralysis x.b x - systemic conditions, syndromes and reactions x.b - antiphospholipid antibodies w/wo the apl syndrome x.j x - systemic conditions, syndromes and reactions x.j - myositis/polymyositis/dpm/rhabdomyolysis/myopathy x.k x - systemic conditions, syndromes and reactions x.k - sarcoid-like, granulomatous thoracic and/or extrathoracic reaction x.s x - systemic conditions, syndromes and reactions x.s - pulmonary/systemic vasculitis/polyangiitis (anca-positive) xv.e xv - pulmonary pathology xv.e - path: ild with a granulomatous component (see also im) xvii.b xvii - infections & related conditions xvii.b - opportunistic pulmonary/systemic infection xvii.c xvii - infections & related conditions xvii.c - aspergillosis, pulmonary xvii.e xvii - infections & related conditions xvii.e - pneumocystis jiroveci pneumonia xvii.f xvii - infections & related conditions xvii.f - tuberculosis, miliary xvii.g xvii - infections & related conditions xvii.g - tuberculosis (pulmonary, extrapulmonary, reactivation or de novo) xvii.z xvii - infections & related conditions xvii.z - histoplamosis (reactivation) xvii.aa xvii - infections & related conditions xvii.aa - coccidioidomycosis 3 adenosine iv.a iv - airway involvement iv.a - bronchospasm - asthma iv.f iv - airway involvement iv.f - severe, catastrophic asthma attack (can be fatal) xi.b xi - miscellaneous xi.b - chest pain (acute - subacute) xii.m xii - cardiovascular involvement / toxicity xii.m - cardiac/cardiopulmonary arrest 2 adenosine 5'-triphosphate xi.b xi - miscellaneous xi.b - chest pain (acute - subacute) 1 adrenaline (epinephrine) ii.a ii - pulmonary edema - ards - acute respiratory failure ii.a - pulmonary edema, noncardiogenic (ncpe) ii.d ii - pulmonary edema - ards - acute respiratory failure ii.d - pulmonary edema, cardiogenic ii.i ii - pulmonary edema - ards - acute respiratory failure ii.i - flash (fulminate) pulmonary edema xi.b xi - miscellaneous xi.b - chest pain (acute - subacute) xi.d xi - miscellaneous xi.d - metabolic acidosis (incl. lactic-). may cause dyspnea xii.e xii - cardiovascular involvement / toxicity xii.e - takotsubo (stress) cardiomyopathy xii.f xii - cardiovascular involvement / toxicity xii.f - cardiomyopathy (acute, subacute, chronic) xii.g xii - cardiovascular involvement / toxicity xii.g - myocardial ischemia, coronary artery disease, myocardial infarction xii.j xii - cardiovascular involvement / toxicity xii.j - myocardial stunning xii.l xii - cardiovascular involvement / toxicity xii.l - cardiac arrhythmias or dysrhythmias (af, vt, vf, tdp) xii.t xii - cardiovascular involvement / toxicity xii.t - torsades de pointe xii.w xii - cardiovascular involvement / toxicity xii.w - asystole xii.af xii - cardiovascular involvement / toxicity xii.af - coronary arterial spasm xii.aq xii - cardiovascular involvement / toxicity xii.aq - wandering pacemaker 3 adrenocorticotropic hormone (acth) xvii.c xvii - infections & related conditions xvii.c - aspergillosis, pulmonary xvii.e xvii - infections & related conditions xvii.e - pneumocystis jiroveci pneumonia 5 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 search search advanced search diagnosing dird 1 drug and radiation history 2 drug singularity - correct identification of the drug 3 consistent timing of exposure v. onset of symptoms 4 clinical, imaging, bal, pathological pattern consistent with the specific drug 5 careful exlusion of another cause 6 remission of symptoms with removal of drug 7 recurrence with rechallenge (rarely advisable) 8 causality assessment more detailed checklist frequency ? - questionable signal 1 < 10 cases 2 10 - 50 cases 3 50 - 100 cases 4 100 - 200 cases 5 >200 cases all patterns ? i interstitial/parenchymal lung disease i.a pneumonitis (ild), acute, severe (see also under ards) i.b pneumonitis (ild) i.c eosinophilic pneumonia (pulmonary infiltrates and eosinophilia) i.d organizing pneumonia (a pattern consistent with) i.e acute eosinophilic pneumonia (aep) i.f acute fibrinous organizing pneumonia (afop) i.g pulmonary fibrosis i.h subclinical pulmonary opacities i.i diffuse pulmonary calcification (calciphylaxis) i.j exogenous lipoid pneumonia i.k lung nodule or nodules i.l diffuse alveolar damage (dad) (see alsoo under iib and xvf) i.m ild with a granulomatous component i.n pulmonary alveolar proteinosis (pap) i.o focal/localized area of pneumonitis/fibrosis i.p progression of preexisting pulmonary lamm i.q nodules in lung parenchyma (a.k.a. nodulosis) i.r amiodarone pulmonary toxicity i.s a mass or masses i.t pneumoconiosis, talcosis i.u relapsing or migrating pneumonitis/pneumonia (see also id) i.v subclinical changes in lung function/pft i.w rapidly progressive ild or pulmonary fibrosis (hamman-rich syndrome) i.x pleuroparenchymal fibroelastosis (ppfe) i.y progression, acceleration or exacerbation of preexisting ild/fibrosis i.z areas of consolidation i.aa delayed ild, -pneumonitis, -fibrosis i.ab radiation-induced lung injury (rili) i.ac acute radiation pneumonitis i.ad radiation recall pneumonitis i.ae interstitial pneumonitis with autoimmune features (ipaf) i.af chemical pneumonitis i.ag fire-eater's lung or -pneumonitis i.ah acute restrictive lung dysfunction i.ai pulmonary fibrosis and emphysema syndrome i.aj shrinking lung syndrome i.ak pleuropneumonitis i.al silicone pneumonitis - 'silicone lung' i.am siliconoma i.an hypersensitivity pneumonitis pattern ii pulmonary edema - ards - acute respiratory failure ii.a pulmonary edema, noncardiogenic (ncpe) ii.b ards ii.c ards and the hemolytic-uremic syndrome (hus) ii.d pulmonary edema, cardiogenic ii.e transfusion-related acute lung injury (trali or -ards) ii.f hypoxemia, low saturation (may occur in isolation) ii.g negative pressure pulmonary edema (nppe) ii.h overload pulmonary edema (including taco) ii.i flash (fulminate) pulmonary edema ii.j transient pulmonary opacities ii.k pulmonary edema/ards of the atra syndrome (see xab) ii.l postoperative ards ii.m pre-engraftment syndrome ii.n engraftment syndrome ii.p ards and divc ii.q respiratory distress iii pulmonary hemorrhage iii.a diffuse alveolar hemorrhage (dah) iii.b pneumorenal syndrome iii.c hemoptysis iii.d alveolar hemorrhage, diffuse, anca-positive or related iii.e pulmonary hematoma iii.f negative pressure pulmonary hemorrhage (npph) iii.g bleeding/hemorrhage from preexisting lung tumor iii.h major/massive hemoptysis iii.i catamenial hemoptysis iii.j anti-gbm-related pneumorenal syndrome and dah (goodpasture) (see under xac) iii.k epistaxis iii.l lobar alveolar hemorrhage iv airway involvement iv.a bronchospasm - asthma iv.b bronchospasm and angioedema iv.c obliterative bronchiolitis (see also ivn) iv.d cough (lone) iv.e cough (acute, violent, explosive) iv.f severe, catastrophic asthma attack (can be fatal) iv.g syncope - cough syncope iv.h airway necrosis iv.i foreign body aspiration bronchiolitis iv.j calcification of tracheobronchial cartilaginous rings iv.k bronchiectasis iv.l bronchial stump dehiscence iv.m bronchial stenosis/stricture iv.n obstructive airway dysfunction (see also ivc) iv.o airway hyperresponsiveness iv.p thermal, chemical or caustic airway injury iv.q reactive airway dysfunction syndrome (rads) iv.r airway pigmentation (black, bluish, petechial) iv.s pill aspiration syndrome iv.t bronchitis, chronic bronchitis, bronchorrhea iv.u endobronchial eosinophilic nodules iv.v deterioration/exacerbation of preexisting asthma or copd iv.w plugs/casts in the airways iv.x transient hacking cough iv.y eosinophilic airways disease/bronchiolitis iv.z bronchial wall erosion/hematoma v pleural and/or pericardial involvement v.a pleural effusion v.b eosinophilic pleural effusion v.c pleural thickening/fibrosis - fibrothorax v.d pleural/pericardial effusion, ana positive (di lupus) v.e hemothorax - serosanguineous pleural effusion v.f pneumothorax v.g effusions of the ovarian hyperstimulation syndrome (ohss) v.h chylothorax v.i pleuritis (may cause acute chest pain (see also under xic) v.j pericardial effusion - tamponade: see under xiic v.k pleural calcifications v.l malignant pleural mesothelioma v.m pleuropericardial effusion (ana unknown or negative) v.n hemopericardium - bloody pericardial effusion v.o the 'folded lung' (blesovsky syndrome) v.p pleuroparenchymal fibroelastosis (ppfe) v.q empyema v.r pleural mass or masses v.s serositis - polyserositis v.t the apical cap v.u eosinophilic pleuritis v.v silicone pleural effusion v.w silicone pleural nodules - pleural siliconomas v.x black pleural effusion vi pulmonary vasculopathy vi.a pulmonary embolism - venous thromboembolism vi.b pulmonary arterial hypertension vi.c pulmonary veno-occlusive disease vi.d pulmonary vasculitis or capillaritis vi.e fat/oil embolism vi.f the hemolytic and uremic syndrome (hus). see also under xaf vi.g foreign body vasculopathy (excipient lung disease) vi.h cement embolism vi.i acute pulmonary hypertension vi.j mercury pulmonary embolism vi.k eosinophilic pulmonary vasculitis vi.l acute pulmonary vasoconstriction and pht vi.m silicone embolism (se) - se syndrome vi.n crystal pulmonary embolism vi.o air/gas embolism vi.p angiomatoid pulmonary vasculopathy vi.q rebound pulmonary arterial hypertension vi.r septic pulmonary embolism vi.t pulmonary artery aneurysm(s) vi.u pulmonary vascular microthrombi vi.v foreign body/substance embolism vi.w worsening of preexisting phtn vi.x pulmonary lymphangiectasis vi.y pulmonary hypertension of the newborn (persistent pht) vi.z pulmonary vein stenosis vi.aa lipiodol pulmonary embolism vi.ab pulmonary artery stenosis vi.ac pulmonary infarction vi.ad right ventricular outflow tract compression vii mediastinal involvement vii.a lymphadenopathy (intrathoracic) vii.b lymphadenopathy with reactive changes vii.c mediastinal lipomatosis vii.d fibrosing mediastinitis vii.e granulomatous mediastinal lymphadenopathy vii.f enlarged thymus vii.g hemomediastinum - mediastinal hematoma vii.h pneumomediastinum vii.i mediastinitis vii.j compression of mediastinal structures/organs vii.k mediastinal silicone infiltration vii.l calcification of mediastinal lymph nodes vii.m malignant lymphoma viii upper, central, large airway involvement viii.a angioedema (may cause uao & asphyxia) viii.b hematoma causing upper airway obstruction viii.c upper airway obstruction other than angioedema or hematoma viii.d thermal (burns, frostbite), chemical, or caustic facial and/or airway injury viii.e laryngospasm (a.k.a. laryngismus) viii.f central airway instability - transient tracheomalacia viii.g tracheal narrowing - sabre sheath trachea viii.h vocal cord dysfunction, adduction, closure viii.i midline destructive lesions viii.j laryngeal disorder: dysphonia, hoarseness viii.k airway fire/explosion viii.k submucosal airway petechiae/hemorrhage viii.m drug foreign body in the airway viii.o perforation of the nasal septum viii.q tongue involvement (edema, hematoma) viii.r tracheal necrosis, chondronecrosis, perforation viii.s endoluminal clotting viii.t vocal cord paralysis viii.u vocal cord hematoma viii.v retropharyngeal hematoma viii.w uvulitis, uvular edema viii.x opportunistic large airway infection (bacterial, fungal, viral) viii.y sinonasal discharge, -blockage, -obstruction viii.z an increased bite force viii.ab tracheal/bronchial fistula viii.ac retropharyngeal emphysema viii.ad osteonecrosis of the jaw viii.ae 'meth mouth' viii.af oromandibular dystonia ix neuromuscular / cns involvement - disordered breathing during sleep ix.a diaphragm/inspiratory muscle weakness/paralysis (w/wo arf) ix.b respiratory dyskinesia ix.c chest wall muscle rigidity - stiff chest - tetany ix.d ventilatory depression-hypoventilation (may cause arf). see also xie ix.e disordered breathing pattern - cheynes-stokes respiration ix.f hiccup ix.g hyperventilation, hypocapnia and alcalosis ix.h dyspnea, unexplained otherwise ix.i respiratory arrest - apnea ix.j phrenic nerve injury - hemidiaphragmatic paralysis ix.k trismus (lockjaw) ix.l hyperpnea, hyperventilation ix.m epidural thoracic lipomatosis ix.n vagal nerve injury ix.o pneumorachis ix.p disordered breathing during sleep ix.q obstructive sleep apneas ix.r myasthenia gravis (may cause neuromuscular arf) ix.s botulism - wound botulism ix.t cns involvement/dysfunction ix.u central sleep apneas ix.v myopathy/muscle weakness or paralysis ix.w diaphragmatic contracture ix.x thoracic epidural or spinal hematoma ix.y a flare or relapse of preexisting myasthenia gravis ix.z hypocalcemia (may lead to respiratory muscle weakness and rf) ix.aa hypophosphatemia (may cause muscle weakness and rf) x systemic conditions, syndromes and reactions x.a dress (drug rash eosinophilia and hypersensitivity syndrome) x.b antiphospholipid antibodies w/wo the apl syndrome x.c capillary/vascular leak syndrome (cls) (see also under xr) x.d lupus - lupus syndrome (see also vd) x.e autoimmunity - autoimmune conditions x.f anaphylaxis x.g hypersensitivity reaction (may involve skin, throat and/or airways) x.h eosinophilic granulomatosis with polyangiitis (churg-strauss) x.i the immune reconstitution syndrome (ircs) x.j myositis/polymyositis/dpm/rhabdomyolysis/myopathy x.k sarcoid-like, granulomatous thoracic and/or extrathoracic reaction x.l systemic granulomatosis other than xk x.m pulmonary and/or systemic vasculitis (anca status mpo, unknown or negative) x.n tumor lysis syndrome (tls) x.o neutrophilic dermatosis (pyoderma, sweet) x.p serum sickness-like reaction x.q systemic inflammatory response x.r fluid retention x.s pulmonary/systemic vasculitis/polyangiitis (anca-positive) x.t jarisch-herxheimer reaction x.u multiple organ dysfunction/failure (mods/mof) x.v systemic eosinophilic syndrome w/wo vasculitis (see also xa) x.w eosinophilia myalgia syndrome (ems) x.x subclinical anca positivity x.y subclinical ana positivity x.z coagulopathy x.aa propofol infusion syndrome (pris) x.ab differentiation- or atra syndrome x.ac anti-gbm antibody disease (goodpasture-like) or flare of x.ad skin purpura, ecchymoses or necrosis x.ae antisynthetase antibodies (asa)-asa syndrome x.af thrombotic microangiopathy (see also under vif) x.ag the serotonin syndrome x.ah granulomatosis with polyangiitis (w/wo anca) or flare of x.ai the ovarian hyperstimulation syndrome (ohs) x.aj polyarteritis nodosa-like condition x.ak dual mpo-/pr3-anca systemic disease/vasculitis x.al drug withdrawal syndrome x.am immune-related adverse effect/toxicity x.an cytokine release syndrome x.ao flare of preexisting anca-related vasculitis x.ap delayed anaphylaxis x.aq relapse or flare of preexisting ulcerative colitis x.ar relapse/flare/onset of crohn's disease x.as scleroderma renal crisis x.at hyperthermia x.au visceral angioedma x.av hypogammaglobulinemia-antibody deficiency (see under xviiw) x.aw connective tissue disease x.ax scleroderma x.ay polymyalgia rheumatica x.az hemophagocytic syndrome xi miscellaneous xi.a cyanosis, a low spo2 and normal measured pao2 (see also xiva, b, e) xi.b chest pain (acute - subacute) xi.c pleuritic chest pain (see also under vi) xi.d metabolic acidosis (incl. lactic-). may cause dyspnea xi.e respiratory acidosis - hypercapnia xi.f pseudocyanotic skin discoloration (see also xia, xiva, xivb) xi.g aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility) xi.h esophageal tear/rupture/fistula xi.i esophageal toxicity xi.j esophageal dysmotility xi.k esophageal hematoma (may cause chest pain and/or tracheal compression) xi.l superior vena cava syndrome xi.m pulmonary emphysema - lung cysts or bullae xi.n neutropenia, agranulocytosis (w/wo infection/sepsis) xi.o pharmacobezoar xi.p chest deformity: platythorax xi.q lung compression from ascites xi.r death following exposure or poisoning xi.s death following inhalation of compound - sniffing death xi.t yellow nail syndrome xi.u chronic chest pain/discomfort xi.v rib fracture xi.w cavitation/necrosis of lung tumor or metastases xi.x addictive risk xi.y adrenal suppression xi.z psychiatric symptoms xi.aa cns symptoms or involvement, stroke xi.ab gingival hypertrophy xi.ac thermal skin/dermal injury xi.ad granulomas on tattoo edges xi.ae barotrauma (incl. pneumothorax, pneumomediastinum, interstitial ephysema...) xi.af refractoriness to epineprine in case of anaphylaxis xi.ag vertebral compression fracture xi.ah fainting - syncope xi.ai cushing syndrome xi.aj congenital respiratory malformations in the fetus xi.ak sialorrhea - drooling xi.al periostitis - rib hypertrophy xi.am rectus abdominis hematoma xi.an disrupted lung surfactant function xi.ao pulmonary laceration / lung trauma xi.ap halitosis - breath malodor xi.aq retroperitoneal fibrosis xi.ar calciphylaxis xii cardiovascular involvement / toxicity xii.a left ventricular dysfunction/failure xii.b valvular heart disease and/or dysfunction xii.c pericarditis, pericardial effusion, tamponade xii.d myocarditis xii.e takotsubo (stress) cardiomyopathy xii.f cardiomyopathy (acute, subacute, chronic) xii.g myocardial ischemia, coronary artery disease, myocardial infarction xii.h eosinophilic myocarditis xii.i endocarditis (infective) xii.j myocardial stunning xii.k pericardial thickening - constrictive pericarditis xii.l cardiac arrhythmias or dysrhythmias (af, vt, vf, tdp) xii.m cardiac/cardiopulmonary arrest xii.n hypotension, shock, cardiovascular collapse xii.o coronary artery disease, chronic xii.p qt prolongation xii.q coarctation of the aorta (acquired) xii.r congestive heart failure xii.s heart block (bundle branch- or av-) xii.t torsades de pointe xii.u left-sided intracavitary thrombosis xii.v hypertrophic cardiomyopathy xii.w asystole xii.x sinus arrest xii.y pneumopericardium xii.z heart valve thrombosis xii.aa arterial (aorta, limb) vasoconstriction and/or ischemia, acute xii.ab pericardial fat necrosis xii.ac right atrial thrombosis xii.ad effusive-constrictive pericarditis xii.ae aortic dissection xii.af coronary arterial spasm xii.ag bradycardia xii.ah tachycardia xii.ai cardiotoxicity xii.aj systemic arterial thrombosis xii.ak late left ventricular dysfunction/failure xii.al hyperkinetic circulation xii.am endocardial fibroelastosis xii.an pericardial calcification xii.ao intracardiac bone cement embolism xii.ap coronary artery dissection xii.aq wandering pacemaker xii.ar calcification of the coronary arteries xii.as giant cell myocarditis xiii neoplastic conditions xiii.a lung cancer xiii.b lymphoproliferative disease (pulmonary, endothoracic) xiii.c lymphadenopathy with reactive changes (see viib) xiii.d malignant mesothelioma (pleural, pericardial) xiii.e breast cancer xiii.f fibromatosis of the chest wall xiii.g lymphomatoid granulomatosis (pulmonary, endothoracic) xiii.h pulmonary nodular lymphoid hyperplasia xiii.i breast implant-associated anaplastic large cell lymphoma xiii.j pulmonary synovial sarcoma xiii.k lymphoproliferative disease (extrathoracic) xiii.l chondrosarcoma xiv hemoglobinopathies-abnormal hemoglobins states (acquired) xiv.a methemoglobinemia xiv.b sulfhemoglobinemia xiv.c carboxyhemoglobinemia xiv.d interference with cohb measurement xiv.e interference with spo2 measurement xiv.f a condition mimicking methemoglobinemia xv pulmonary pathology xv.a path: cellular nsip pattern (see also ia, ib) xv.b path: eosinophilic pneumonia (subacute or acute) (see also ic) xv.c path: organizing pneumonia (op/boop) pattern (see also id) xv.d path: acute fibrinous organizing pneumonia (afop-pattern) (see also if) xv.e path: ild with a granulomatous component (see also im) xv.f path: diffuse alveolar damage (dad-pattern) (see also il) xv.g path: alveolar hemorrhage (see also iiia) xv.h path: fibrotic nsip pattern xv.i path: pneumocyte atypia (reactive epithelial cells) xv.j path: pulmonary fibrosis (uip-pattern) xv.k path: desquamative interstitial pneumonia (dip-pattern) xv.l path: pulmonary fibrosis, unclassifiable xv.m path: lymphoid hyperplasia - lip-pattern xv.n path: pulmonary alveolar proteinosis pattern (pap pattern) xv.o path: endogenous lipoid pneumonia (phospholipidosis) xv.p path: exogenous lipoid pneumonia xv.q path: foreign body deposits/reaction xv.r path: smudged geographic necrosis xv.s path: pneumoconiosis (silicosis, talcosis, talcoma) xv.t path: pulmonary amyloid deposits xv.u path: crystal storage disease xv.v path: diffuse pulmonary calcification xv.w path: pulmonary edema (see also ii/iia) xv.x path: acute or subacute bronchiolitis (see also ivc, ivi) xv.y path: respiratory bronchiolitis (rb-ild-pattern) xv.z path: chronic obliterative broncholitis (see also ivc, ivn) xv.aa path: foreign body bronchiolitis (see also ivi) xv.ab path: pulmonary capillaritis (see also iiia, xm, xs) xv.ac path: pulmonary vasculitis other than capillaritis xv.ad path: eosinophilic vasculitis xv.ae path: lipid/fat embolism (see also vie) xv.af path: granulomatous pulmonary vasculitis xv.ag path: foreign body embolism, microangiopathy, vasculopathy xv.ah path: pulmonary congestion xv.ai path: cement (acrylate) pulmonary embolism xv.aj path: cholesterol crystal embolism xv.ak path: pulmonary veno-occlusive disease (pvod) xv.al path: pulmonary hypertension incl. angiomatoid vasculopathy xv.am path: thrombosis in pulmonary arterioles/venules xv.an path: eosinophilic pleuritis xv.ao path: pleuritis, pleural fibrosis xv.ap path: pleuroparenchymal fibrosis/fibroelastosis (ppfe) xv.aq path: resin (kayexalate-sevelamer) lung xv.ar path: barium lung xv.as path: fire eater's lung xv.at path: pulmonary capillary granulocyte sequestration xv.au path: progession of pulmonary lamm xv.av path: textiloma - gossypiboma xv.aw path: skin vasculopathy/vasculitis xv.ax path: focal organizing pneumonia xv.ay path: smoking-related interstitial fibrosis (srif). respiratory bronchiolitis with fibrosis xv.az path: lymphadenopathy with reactive changes xv.ba path: granulomatous lymphadenopathy xv.bb path: airway inflammation xv.bc path: opportunistic pulmonary infection (see also xvii/xviib-d-e) xv.bd path: bronchiolar vasculitis and necrosis xv.be path: interstitial pulmonary edema xv.bf path: pulmonary necrotizing granuloma xv.bg path: tracheal or bronchial wall ulceration (see also ivs) xv.bh path: foreign body reaction in large airway walls xv.bi path: giant-cell interstitial pneumonia (gip)-pattern xv.bj path: alveolar carbonaceous material or deposits xv.bk path: stainable iron in airway wall (see also ivs) xv.bl path: resolving alveolar damage xv.bm path: diffuse lymphangiectasis xv.bn path: silicone in lung tissue, pulmonary vasculature or pleura xv.bo path: siliconoma xv.bp path: post-transplant lymphoproliferative disease (ptld) xv.bq path: lymphoproliferative disease, endothoracic xv.br path: lymphomatoid granulomatosis xv.bs path: striated heart muscle damage xv.bt path: histiocytic proliferation xv.bu path: pulmonary peliosis xv.bv path: pulmonary cytolytic thrombi xv.bw path: airspace enlargement with fibrosis xv.bx path: elemental (fluid, metallic) mercury embolism xvi imaging xvi.a imaging: diffuse haze xvi.b imaging: ground-glass shadowing/opacities (ggo) xvi.c imaging: a mosaic pattern of attenuation xvi.d imaging: alveolar opacities with a batwing or butterfly distribution xvi.e imaging: pulmonary opacities with a subpleural distribution xvi.f imaging: bibasilar opacities/shadowing xvi.g imaging: diffuse whiteout xvi.h imaging: biapical or mid-lung opacities xvi.i imaging: an area or areas of involvement with a recognizable anatomic distribution xvi.j imaging: wandering (migratory) pulmonary opacities xvi.k imaging: an area or areas of consolidation xvi.l imaging: peribronchovascular areas of consolidation xvi.m imaging: interlobular septal thickening xvi.n imaging: intralobular septal thickening - crazy paving xvi.o imaging: localized ground-glass xvi.p imaging: small irregular opacities - ila - diffuse reticulation xvi.q imaging: a pattern similar/consistent to/with ipf xvi.r imaging: an area or areas of involvement with low attenuation numbers xvi.s imaging: an area or areas of involvement with high attenuation numbers or metallic density xvi.t imaging: diffuse pulmonary calcification xvi.u imaging: a miliary pattern (diffuse random micronodules) xvi.v imaging: diffuse centrilobular micronodules xvi.w imaging: lung nodule or several nodules xvi.x imaging: the 'halo' sign xvi.y imaging: reversed halo or 'atoll' sign xvi.z imaging: a large nodule or mass xvi.aa imaging: nodules, mass or masses with a central area of low attenuation (see also under xviaa) xvi.ab imaging: cavitating lung nodules (see also iq, xis, xiii, xviaa and xviip) xvi.ac imaging: a generalized increase in lung density xvi.ad imaging: a calcified mass or masses xvi.ae imaging: a pattern similar to progressive massive fibrosis (pmf) xvi.af imaging: lung cysts or bullae (see also xvi ah/bf) xvi.ag imaging: pulmonary emphysema xvi.ah imaging: pneumatoceles (see also xviaf) xvi.ai imaging: a 'tree-in-bud' pattern xvi.aj imaging: bronchiectasis xvi.ak imaging: calcification of cartilaginous rings xvi.al imaging: bronchial wall thickening xvi.am imaging: contrast tracheo- and/or bronchogram xvi.an imaging: pleural effusion xvi.ao imaging: massive pleural effusion xvi.ap imaging: pleural thickening xvi.aq imaging: pneumothorax xvi.ar imaging: hydropneumothorax xvi.as imaging: pleural mass or masses xvi.at imaging: subpleural fat deposits xvi.au imaging: mediastinal fatty deposits xvi.av imaging: displacement/migration of breast implant xvi.aw imaging: migration of foreign body in the pulmonary circulation xvi.ax imaging: foreign body pulmonary embolism xvi.ay imaging: asymmetrical, predominantly unilateral involvement xvi.az imaging: solitary pulmonary nodule xvi.ba imaging: pulmonary parenchymal calcification(s) xvi.bb imaging: pneumomediastinum xvi.bc imaging: intrathoracic lymph node enlargement xvi.bd imaging: pneumorachis xvi.be imaging: enlarged thoracic venous collaterals xvi.bf imaging: tumoral cavitation xvi.bg imaging: pulmonary vein stenosis xvi.bh imaging: f18-pet scan positive lympadenopathy xvi.bi imaging: hyperlucent lung xvi.bj imaging: atelectasis (a combination of increased density and volume loss. typically lobar) xvi.bk imaging: thoracic musculoskeletal abnormalities xvi.bl imaging: avid lung uptake on pet-scan xvi.bm imaging: avid pleural uptake on pet-scan xvii infections & related conditions xvii.a pneumonia - respiratory tract infection xvii.b opportunistic pulmonary/systemic infection xvii.c aspergillosis, pulmonary xvii.d pneumocystis jiroveci pulmonary colonization xvii.e pneumocystis jiroveci pneumonia xvii.f tuberculosis, miliary xvii.g tuberculosis (pulmonary, extrapulmonary, reactivation or de novo) xvii.h nontuberculous mycobacterial infection xvii.i m. bovis (bcg) infection (topical - systemic) xvii.j mucormycosis (pulmonary, tracheobronchial or systemic) xvii.k bacterial airway colonization xvii.l scedosporium pulmonary infection xvii.m fungal airway infection xvii.n legionella pneumophila pneumonia xvii.o nocardia pulmonary infection xvii.p lung abscess/abscesses (see also vir) xvii.q viral pneumonia xvii.r fungal infection (pulmonary/extrapulmonary) xvii.s sternoclavicular septic arthritis xvii.u epidural abscess xvii.v strongyloides stercoralis hyperinfection (w/wo dah) xvii.w hypogammaglobulinemia - antibody deficiency xvii.x aspergillus airway colonization xvii.y cryptococcus neoformans pulmonary infection xvii.z histoplamosis (reactivation) xvii.aa coccidioidomycosis xvii.ab protozoan infection (incl. leishmaniasis) xvii.ac actinomycosis xvii.ad systemic infection (transmitted) xvii.ae botulism, wound botulism (see under ixs) xvii.af reactivation of a prior pulmonary infection (tb, melioidosis) xvii.ag cmv pneumonitis (reactivation) xvii.ah pulmonary pasteurellosis xvii.ai a falsely negative/indeterminate igra test result xvii.aj bordetella bronchiseptica pulmonary infection xviii distinctive patterns - 'eye-catchers' xviii.a eye catcher: contrast tracheo- and/or bronchogram xviii.b eye catcher: electron-dense area or areas of consolidation on unenhanced ct xviii.c eye catcher: a displaced breast implant xviii.d eye catcher: mercury embolism xviii.e eye-catcher: multiple radiolucent balls xviii.f eye-catcher: tongue edema xviii.g eye-catcher: cement embolism xviii.h eye-catcher: lipiodol embolism xviii.i eye-catcher: tracer-avid pleural area or areas on pet-scan xviii.j eye-catcher: avid lung uptake on pet-scan xviii.k eye-catcher: an electron-dense liver on unenhanced ct xviii.l eye catcher: candy-cane esophagus xviii.m eye catcher: pneumorachis xviii.n eye-catcher: periostitis - rib hypertrophy xviii.o eye-catcher: drug-induced musculoskeletal abnormalities xviii.p eye-catcher: an electron-dense ('white') thyroid xix cytology, biochemistry of bal, pleural fluid or fna xix.a bal: an excess proportion of lymphocytes xix.b bal: an excess proportion of neutrophils xix.c bal: an excess proportion of eosinophils xix.d bal: gross or microscopic bleeding/hemorrhage xix.e bal: stainable iron in macrophages xix.f bal: foamy macrophages in bal, pleural fluid, or fna xix.g bal: atypical epithelial cells xix.h bal: lipid vacuoles in bal alveolar macrophages xix.i bal: multinucleated giant cells xix.j bal: free exogenous lipids in supernatant xix.k bal: talc crystals in macrophages or lying free in balf xix.l bal: silicone globules in macrophages xix.m bal: a normal cell differential xix.n cytology: brown-pigmented macrophages xx pediatric drug-induced & iatrogenic respiratory disease xxi rechallenge data xxi.a has led to fatal relapse xxi.b has led to relapse. no fatalities recorded yet xxi.c tolerance can be induced successfully xxi.d rechallenge can be monitored using biomarker latest news sun, 06 may 2018 07:43:11 current issues thu, 15 mar 2018 16:12:47 diagnosing dird: a new feature in pneumotox ! tue, 06 feb 2018 05:48:16 pneumotox for tablets and smartphones sat, 23 apr 2016 10:53:25 warning ! is the literature becoming less reliable? fri, 22 may 2015 14:24:09 alerts. new drug casualties latest changelog 16/05/2018 - 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Domain Name: PNEUMOTOX.COM
Registry Domain ID: 513457_DOMAIN_COM-VRSN
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